What causes acne on your cheeks? July 31, 2019 14:40 The cheeks can be one of the most bothersome places to have acne. Click here to learn more about why cheek acne appears and what you can do to avoid it. Related articles Why can’t I just exfoliate with a washcloth? What ingredients should I avoid in an acne cream? What is over-exfoliation? Why is SPF in moisturizer important?